How do you make and test new materials that will not be rejected by the body when used as implants?

Question: How do you make and test new materials that will not be rejected by the body when used as implants?
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Asked by JanaSw to Baljit on 19 Nov 2015.
- Baljit Ghatora answered on 19 Nov 2015:
  
  @janasw- an interesting question from an aspiring biomedical student. I firstly need to find what environment in the body would the implant be exposed to- for example the eye fluids are the aqueous humour. I would find the chemicals that exist and make this artificially in the lab. This is known as in vitro analysis.

Question: How do you make and test new materials that will not be rejected by the body when used as implants?