How do you test things ,has it ever heart anyone if you do it on people?

Question: How do you test things ,has it ever heart anyone if you do it on people?
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Asked by 827sped32 to Baljit, Michael, Arlene on 9 Nov 2015. This question was also asked by Paige.
- Baljit Ghatora answered on 9 Nov 2015:
  
  A lot of the research I do is carried out on testing samples in simulated solutions…basically these are nifty solutions that mimic body fluids. I make these myself to be the same concentration as body fluids. I am interested in eye fluids…
- Michael Kyriakides answered on 10 Nov 2015:
  
  @827sped32 – I usually conduct experiments on samples provided by people (such as blood or urine) but never on the actual person. It is generally not allowed to cause serious damage on a person while doing research.

Question: How do you test things ,has it ever heart anyone if you do it on people?